王懿春，教授、主任医师，医学博士，博士生导师。现任重症医学科主任兼学科带头人，学术任职中国抗癌协会肿瘤重症医学专业委员会常委、中国病理生理学会休克委员会委员、中国医药教育协会血栓与止血危重病专业委员会委员、广东省基层医药学会重症医学专委员副主任委员、广东省医学会重症医学分会常委、广东省医师协会休克专业委员会常委、广州市医学会重症医学分会副主任委员、广州市医师协会危重病医师分会副主任委员等职务。先后多次获得湖南省医学科技二等奖和三等奖，获得湖南省医学会和广州市医学会优秀学术论文二等奖和三等奖。入选湖南省新世纪121人才工程、湖南省高层次卫生人才“225”工程人选，并获得20届国家青年文明号号手，羊城好医生等荣誉称号。
1995年毕业于衡阳医学院，2004年硕士和2011年博士就读于中南大学麻醉学专业，2014年和2018年作为访问学者访问美国SUNY上州医科大学医院和美国MD安德森癌症医学中心麻醉和ICU。从事麻醉和危重病救治临床工作30多年，对危重症疾病的诊断、治疗具有丰富的实际工作经验。主要进行重症感染和多器官功能障碍综合征中肺保护机制研究，尤其专注于肺损伤相关的分子机制及治疗研究，另外在重症感染和危重症患者数据库建立等人工智能方面有一定的研究经验和工作基础。
近年来主持和参与国家科技部重点专项和国家自然科学基金2项，广东省自然科学基金面上、广州市重点研发项目各1项，省、市级面上项目8项。近五年以第一或通讯作者发表SCI文章20篇，其中中科院分区2区以上5篇，累计被引次数为300余次，授权（申请）国家发明专利4项，编写论著4部，参与制定指南1部。
代表性期刊论文如下：
(1) Wang Yichun;Chen Diyu;Xie Han;Zhou Shuhua;Jia Mingwang;He xiaobo;Guo Feifei;Lai Yihuan;Tang Xiao Xiao;LncRNA GAS5 suppresses TGF-β1-induced transformation of pulmonary pericytes into myofibroblasts by recruiting KDM5B and promoting H3K4me2/3 demethylation of the PDGFRα/β promoter, Molecular Medicine, 2023, Marc 29(1): 32
(2) Wang YC,Chen DL,Xie H,Jia MW,Sun XF,Peng F,Guo FF,Tang DL.AUF1 protects AECs from ferroptosis and alleviates sepsis-induced acute lung injury by regulating NRF2 and ATF3.Cellular and Molecular Life Sciences,2022, Apr 7;79(5):228
(3) Jia Mingwang ,Gan Zhaohui,Luo Xitu,Xie Han,Wang Yichun* ,Dunjin Chen. Successful extracorporeal cardiopulmonary resuscitation for a puerpera with amniotic fluid embolism.Int J Gynaecol Obstet,2021,154(2):372-374
(4) Wang YC, Xie H, Zhang YC, Meng QH, Xiong MM, Jia MW, Peng F, Tang DL.Exosomal miR-107 antagonizes pro-fibrotic phenotypes of pericytes by targeting a pathway involving HIF-1α/Notch1/PDGFRβ/YAP1/Twist1 axis.Am J Physiol Heart Circ Physiol. 2021 Feb 1;320(2):H520-H534
(5) Xie H, Gao YM, Zhang YC, Jia MW, Peng F, Meng QH, Wang YC*.Low let-7d exosomes from pulmonary vascular endothelial cells drive lung pericyte fibrosis through the TGFβRI/FoxM1/Smad/β-catenin pathway.J Cell Mol Med. 2020 Dec;24(23):13913-13926
(6) Li J#, Wang Y#, Zeng Y#, Song T, Pan X, Jia M, He F, Hou L, Li B#, He S#, Chen D#.Critically ill pregnant patient with COVID-19 and neonatal death within two hours of birth.Int J Gynaecol Obstet. 2020 Jul;150(1):126-128
(7) Wang yichun;chen qiong;luo junming;nie jing;meng qinghe;shuai wei,xie han,xia jiamei wang hui,Notch1 promotes the pericytemyofibroblast transition in idiopathic pulmonary fibrosis through the PDGFR/ROCK1 signal pathway,Experimental & Molecular Medicine,2019 Mar 20;51(3):1-11
(8) Luo J, Peng S, Bai W, Wu Z, Shan Z, Wu Z, Yuan X, Che X, Duan Z, Peng J, Wang Y*,Zhang S*.Matrilin-2 prevents the TNFα-induced apoptosis of WB-F344 cells via Suppressing JNK pathway,Biotechnol Appl Biochem. 2019 May;66(3):309-315
(9) Wang Yichun ; Dong Jing; Nie Jing; Zhu Jixiang; Wang Hui; Chen Qiong; Chen Junyi; Xia Jiamei; Shuai Wei, Amelioration of bleomycin-induced pulmonary fibrosis by chlorogenic acid through endoplasmic reticulum stress inhibition,Apoptosis,2017.07.04,22(9): 1147~1156
(10) Wang Yichun ; LiangYing; Luo Junming; Nie Jing; Yin Huiming ; Chen Qiong; Dong Jing; Zhu Jixiang; Xia Jiamei; Shuai Wei, XIST/miR-139 axis regulates bleomycin (BLM)-induced extracellular matrix (ECM) and pulmonary fibrosis through β-catenin, Oncotarget, 2017.05.31, 8(39):65359~65369
(11) Luo Junming ; Cao Falong; Meng Chen; Lin Lijun; Ma Siqing; PengShaohua; Gao Hongling; Javidiparsijani Sara; Wang Guirong; Zhang Menglan; XinJianuo; Wang Yichun*; Zhang Shukun*,Clinicopathological and molecularcharacteristics of synchronous gastric adenocarcinoma and gastrointestinal stromal tumors, Scientific Reports, 2017.10.10, 7(1): 12890~12890
(12) Wang YC ; Liu JS; Tang HK; Nie J; Zhu JX; Wen LL; Guo QL ,MiR-221tar gets HMGA2 to inhibit bleomycin-induced pulmonary fibrosis by regulatingTGF-β1/Smad3 induced EMT, Int J Mol Med, 2016.10.30, 38(4):1208~1216
(13) Wang Yichun ; Liu Jingshi; Chen Junyi; Feng Tao; Guo Qulian ,MiR-29 mediates TGFbeta 1-induced extracellular matrix synthesis through activation of Wnt/beta -catenin pathway in human pulmonary fibroblasts, Technol Health Care, 2015.01.01, 23 Suppl 1(1): S119~S125
(14) Wang YC ; Liu JS; Chen JY; Wu SQ; Wang GR; Nie J; Zhang SK; Guo QL ;Luo JM, Multiple functions of the first EGF domain in matrilin-3: Secretion and endoplasmic reticulum stress., Int J Mol Med, 2015.10.15, 36(6): 1648~1656
(15) Wang Y, Tang H, Guo Q,et al.Effects of Intravenous Patient-Controlled Sufentanil Analgesia and Music Therapy on Pain and Hemodynamics After Surgery for Lung Cancer: A Randomized Parallel Study.J Altern Complement Med.2015 ,21(11):667-72.
